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Home / Primary Antibodies / Phospho Antibodies

Anti-EIF2S2 Antibody BHA11304739

SKU : BHA11304739

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Mfr.No.	BS64038
Alternative Names	Eukaryotic translation initiation factor 2 subunit 2 ; Eukaryotic translation initiation factor 2 subunit beta ; eIF-2-beta ; EIF2S2 ; EIF2B
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	20q11.22
Clonality	polyclonal
Description	The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF2 exists as a heterotrimeric complex of eIF2α, eIF2ß and eIF2γ. eIF2 functions in the early stages of protein synthesis, by forming a teary complex with GTP and tRNA. This complex binds to the 40S ribosomal subunit, followed by mRNA binding to 40S to form the 43S preinitiation complex, the release of eIF2 from 40S, and the hydrolysis of GTP. Phosphorylation of eIF2a correlates with inhibition of translation initiation .
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human EIF2S2 around the phosphorylation site of ser67.
Modification	phospho-S67
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P20042
Uniprot	P20042
Weight	38 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: p-EIF2S2 (S67) polyclonal antibody detects endogenous levels of EIF2S2 protein only when phosphorylated at Ser67.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304739	BS64038	50µl	$199.33		Add to Cart
BHA11304739	BS64038	100µl	$314.89		Add to Cart

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