Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.
Host
Mouse
Immunogen
Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt’s lymphoma sera
Positive Control
EBV-infected cells or tissues
Reactivity
EBV
Recombinant
FALSE
Regulatory
RUO
Swissprot
Not Applicable
Uniprot
Not Applicable
Gene Id
Not Applicable
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
IF
Description
Optimal dilution for a specific application should be determined., IF
Dilution
IF
0.5-1μg/ml
Reviews of Anti-EBV Early Antigens (Epstein Barr Virus Ea) Antibody BHA10207049