Anti-Chromogranin A / CHGA Antibody BHA10200431

Mfr.No.	1113-MSM6-P1ABX
Alternative Names	Beta-Granin ; CGA ; CHGA ; Chromogranin A Parathyroid Secretory Protein 1 ; ER-37 ; Pancreastatin ; Parastatin ; Parathyroid Secretory Protein 1 ; Pituitary Secretory Protein I ; SP-I
Categories	Primary Antibodies
Cellular Localization	Finely granular cytoplasmic
Chromosome Location	14q32.12
Clonality	Monoclonal
Description	Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Host	Mouse
Immunogen	Recombinant human chromogranin A protein
Isotype	IgG2a Kappa
Positive Control	PC12 cells. Adrenal gland, bowel, thyroid, pancreas, or pheochromocytoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P10645
Uniprot	150793
Gene Id	1113

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution