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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CDK5 Antibody BHA11309045

SKU : BHA11309045

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Mfr.No.	MB0101
Alternative Names	Cdk 5 ; Cdk5 ; CDK5 ; Cell division protein kinase 5 ; Crk6 ; Cyclin dependent kinase 5 ; Cyclin-dependent kinase 5 ; Protein kinase CDK5 splicing ; PSSALRE ; Serine threonine protein kinase PSSALRE ; Serine/threonine-protein kinase PSSALRE ; Tau protein kinase II catalytic subunit ; TPKII catalytic subunit
Antigen	CDK5
Categories	Primary Antibodies
Chromosome Location	7q36.1
Clonality	monoclonal
Description	Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Several Cdk proteins have been identified, including Cdk2-Cdk8, PCTAIRE-1–3, PITALRE and PITSLRE. Cdk5 is thought to be involved in the G1-S transition of the cell cycle and is highly expressed in mature neurons. Activity of Cdk5 increases significantly during neuronal differentiation. Cdk5 has been postulated to be a neurofilament or tau protein kinase, based on its ability to phosphorylate these proteins in vitro.
Host	Mouse
Immunogen	Synthetic peptide, corresponding to the N-terminus of Human CDK5.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q00535
Uniprot	Q00535
Weight	Predicted band size:36KDa Observed band size:36KDa

Description	Product: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol Specificity: This antibody detects endogenous levels of CDK5 and does not cross-react with related proteins
Purity	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, ICC

Description

WB ; ICC

Dilution

WB	1:1000
ICC	1:100-200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11309045	MB0101	50µl	$234.89		Add to Cart
BHA11309045	MB0101	100µl	$368.22		Add to Cart

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