Anti-CD71 / Transferrin Receptor (TFRC) (Extracellular Domain) Antibody BHA10205180

Mfr.No.	7037-MSM7-P0
Alternative Names	Mtvr-1 ; p90 ; TFR1 ; TFRC transferrin receptor (p90 CD71) ; TRFR
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	3q29
Clonality	Monoclonal
Description	It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
Host	Mouse
Immunogen	Recombinant human TFRC protein fragment (aa94-212) (exact sequence is proprietary)
Isotype	IgG2b Kappa
Positive Control	PC3 cells. Human placenta or breast carcinoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P02786
Uniprot	529618
Gene Id	7037

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

ELISA, FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) ,Western Blotting (0.5-1.0μg/ml),Optimal dilution for a specific application should be determined., ELISA ; FACS ; IF ; IHC-F

Dilution

ELISA	Use Ab at 2-4μg/ml for coating
FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205180	7037-MSM7-P0	20µg	$204.67		Add to Cart
BHA10205180	7037-MSM7-P0	100µg	$393.20		Add to Cart

Anti-CD71 / Transferrin Receptor (TFRC) (Extracellular Domain) Antibody BHA10205180

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