Anti-CD70 / TNFSF7 Antibody BHA10206834

Mfr.No.	970-MSM1-P1ABX
Alternative Names	CD27 ligand (CD27L) ; CD27LG ; Ki24 ; Surface antigen CD70 ; Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7)
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	19p13
Clonality	Monoclonal
Description	It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown toĀinhibit T cell proliferation induced by dendritic cells.
Host	Mouse
Immunogen	Human WM-1 (Waldenstrom s macroglobulinemia) cell line
Positive Control	Raji cells. Lymph node or tonsil.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P32970
Uniprot	501497; 715224
Gene Id	970

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

ELISA, FACS, IF, IP, IHC-(f)

Description

Inhibits T cell proliferation induced by dendritic cells (Order Ab without Azide).Optimal dilution for a specific application should be determined., ELISA ; FACS ; IF ; IP ; IHC-(f)

Dilution

ELISA	For coating, order Ab without BSA
FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IP	0.5-1 �g/500ug protein Lysate
IHC-(f)	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206834	970-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-CD70 / TNFSF7 Antibody BHA10206834

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