Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.
Host
Mouse
Immunogen
Human peripheral blood mononuclear cells
Isotype
IgM Kappa
Positive Control
CCRF-CEM Cells. Lymph node or Tonsil
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
Q9P2W7
Uniprot
381050
Gene Id
27087
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
IF, IHC-F, IHC(fro)
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., IF ; IHC-F ; IHC(fro)
Dilution
IF
0.5-1μg/ml
IHC-F
2-4μg/ml for 30 minutes at RT
IHC(fro)
Reviews of Anti-CD57 / B3GAT1 Antibody BHA10201485