Anti-CD56 / NCAM1 / NKH1 Antibody BHA10203712

Mfr.No.	4684-MSM2X-P1ABX
Alternative Names	NCAM ; Leu-19 ; NKH1 ; MSK39 ; NCAM120 ; NCAM140 ; NCAM180 ; Neural Cell Adhesion Molecule
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	11q23.1
Clonality	monoclonal
Description	This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Host	Mouse
Immunogen	Membrane preparation of a small cell lung carcinoma
Isotype	IgG1 Kappa
Positive Control	Cerebellum, Pancreas, Neuroblastoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P13591; P13592
Uniprot	503878
Gene Id	4684

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., IF ; IHC-F

Dilution

IF	1-2μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203712	4684-MSM2X-P1ABX	100µg	$393.20		Add to Cart

Anti-CD56 / NCAM1 / NKH1 Antibody BHA10203712

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