Anti-Carcinoembryonic Antigen (CEA) / CD66 Antibody BHA10200240

Mfr.No.	1048-MSM8-P1ABX
Alternative Names	Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 ; CEACAM5 ; CD66 ; Biliary Glycoprotein (BGP-1)
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Luminal surface
Chromosome Location	19q13.1-19q13.2
Clonality	Monoclonal
Description	This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.Ā
Host	Mouse
Immunogen	Recombinant full-length human CEA protein
Isotype	IgG1 Kappa
Positive Control	MCF7 or 293T cells. Colon carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P06731
Uniprot	709196
Gene Id	1048; 634

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	0.25-0.5μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200240	1048-MSM8-P1ABX	100µg	$393.20		Add to Cart

Anti-Carcinoembryonic Antigen (CEA) / CD66 Antibody BHA10200240

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