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Home / Antibodies

Anti-Calmodulin Antibody BHA11300132

SKU : BHA11300132

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Mfr.No.	AP0774
Alternative Names	PPARGC1A ; LEM6 ; PGC1 ; PGC1A ; PGC-1v ; PPARGC1 ; PGC-1(alpha) ; PGC-1α ; PGC1α
Categories	Primary Antibodies
Chromosome Location	4p15.2
Clonality	polyclonal
Description	PPARγ coactivator-1α (PGC-1α) was originally identified as a transcriptional coactivator whose expression closely correlated with adaptive thermogenesis following exposure to cold temperatures. Named for its association with the nuclear receptor peroxisome-proliferator activated receptor (PPARγ), PGC-1α interacts with a diverse array of transcription factors to regulate numerous aspects of cell physiology. PGC-1α helps to regulate cell processes important in adaptive thermogenesis and energy metabolism, including the related functions of glucose uptake, gluconeogenesis, insulin secretion, and mitochondrial biogenesis. Long thought to be a potential therapeutic target for the treatment of type II diabetes, obesity, cardiomyopathy, or other metabolic disorders, a recent functional survey found no obvious differences in PPARγ activity associated with recognized PGC-1α variants.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human PRGC1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9UBK2
Uniprot	Q9UBK2
Weight	91 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. Specificity: PRGC1 (K87) polyclonal antibody detects endogenous levels of PRGC1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300132	AP0774	50µl	$190.44		Add to Cart
BHA11300132	AP0774	100µl	$294.44		Add to Cart

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