A transferase ; ABO ; B transferase ; CD173 ; Fucosylglycoprotein 3-alpha-galactosyltransferase ; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase ; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase ; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase ; Histo-blood group A transferase ; Histo-blood group B transferase
Categories
Primary Antibodies
Cellular Localization
Cell Surface
Chromosome Location
9q34.2
Clonality
monoclonal
Description
Recognizes the blood group H type 2 antigens, trisaccharide FucĪ �1-2GalĪ �1-4GlcNAcĪ �1 of human origin. This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.
Host
Mouse
Immunogen
Mucinous colonic adenocarcinoma
Isotype
IgM Kappa
Positive Control
KG1 cells or human colorectal carcinoma.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P16442
Uniprot
654423
Gene Id
28
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
IF, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., IF ; IHC-F
Dilution
IF
0.5-1μg/ml
IHC-F
0.5-1.0μg/ml for 30 minutes at RT
Reviews of Anti-Blood Group Antigen H Type 2 (CD173) Antibody BHA10201592