Anti-Blood Group Antigen A (CD173) Antibody BHA10201598

Mfr.No.	28-MSM10-P1ABX
Alternative Names	A transferase ; ABO ; B transferase ; CD173 ; Fucosylglycoprotein 3-alpha-galactosyltransferase ; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase ; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase ; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase ; Histo-blood group A transferase ; Histo-blood group B transferase
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	9q34.2
Clonality	monoclonal
Description	This MAb preferably reacts with determinants of chain A and H type 3Ā(Gal1-3GalNAc-R) and 4 (Gal1-3GalNAc-R), but not with type 1 and 2 chain structures. It is not reactive with immuno-dominant A trisaccharide. This MAb is applicable for tissue staining in tumor patients with blood groups A and AB. It shows a highly heterogeneous reactivity in human colon tumor tissue and adjacent mucosa. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Host	Mouse
Immunogen	Mucin isolated from an ovarian cyst fluid
Isotype	IgG1 Kappa
Positive Control	KG1 cells or human colorectal carcinoma tissues.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P16442
Uniprot	654423
Gene Id	28

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., IF ; IHC-F

Dilution

IF	0.5-1μg/ml
IHC-F	0.5-1.0μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201598	28-MSM10-P1ABX	100µg	$393.20		Add to Cart

Anti-Blood Group Antigen A (CD173) Antibody BHA10201598

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