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Home / Primary Antibodies / IHC Antibodies

Anti-BCL2L1 Antibody BHA11302539

SKU : BHA11302539

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Mfr.No.	BS4295
Alternative Names	Bcl-2-like protein 1 ; Bcl2-L-1 ; Apoptosis regulator Bcl-X ; BCL2L1 ; BCL2L ; BCLX ; Bcl-xL ; Bcl-XS ; BclxL ; BclXS
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	20q11.21
Clonality	polyclonal
Description	Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3-dependent cell line, and Bax also counters the death repressor activity of Bcl-2. Bcl-x, one of several additional proteins with sequence homology to Bcl-2, is expressed as Bcl-xL, a 233 amino acid protein with 43% sequence identity with Bcl-2 that suppresses cell death, and Bcl-xS, a shorter variant that is 178 amino acids in length and lacks a 63 amino acid region (amino acids 126-188) found in Bcl-xL and which functions as a dominant inhibitor of Bcl-2. A further apoptosis-inducing protein, Bad, dimerizes both with Bcl-xL and to a lesser extent with Bcl-2, thus displacing Bax and inducing apoptosis
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human Bcl-X around the phosphorylation site of Threonine 47.
Modification	phospho-T47
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q07817
Uniprot	Q07817
Weight	26 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-Bcl-X (T47) polyclonal antibody detects endogenous levels of Bcl-X protein only when phosphorylated at Thr47.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302539	BS4295	50µl	$199.33		Add to Cart
BHA11302539	BS4295	100µl	$314.89		Add to Cart

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