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Home / Primary Antibodies / Phospho Antibodies

Anti-AKT2 Antibody BHA11302660

SKU : BHA11302660

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Mfr.No.	BS4720
Alternative Names	RAC-beta serine/threonine-protein kinase ; Protein kinase Akt-2 ; Protein kinase B beta ; PKB beta ; RAC-PK-beta ; AKT2 ; PKBβ
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	19q13.2
Clonality	polyclonal
Description	AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human AKT2 around the phosphorylation site of Serine 474.
Modification	phospho-S474
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P31751
Uniprot	P31751
Weight	60 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-AKT2 (S474) polyclonal antibody detects endogenous levels of AKT2 protein only when phosphorylated at Ser474.This antibody does not cross-react with AKT1 and AKT3 protein when phosphorylated at the corresponding residues.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302660	BS4720	50µl	$199.33		Add to Cart
BHA11302660	BS4720	100µl	$314.89		Add to Cart

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