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Ube3a-KO

SKU : BHAM00347

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-200599
Description	Model Description: Exon 5 of Ube3a gene was deleted to generate Ube3a knockout mice. Official Symbol: Ube3a NCBI ID: 22215 MGI ID: 105098 Ensembl ID: ENSMUSG00000025326 Pubmed: Ube3a Human Ortholog: UBE3A
Nomenclature	C57BL/6JSmoc-Ube3a^em1Smoc
Exon	Exon 5
Application	Diseases Associated With Ube3A Include Angelman Syndrome And Angelman Syndrome Due To A Point Mutation.
Disease	Angelman Syndrome
Disease	Rare Disease
KI/KO Gene	Ube3a
Synonyms	Hpve6a, 4732496B02, 5830462N02Rik, A130086L21Rik

Reference	MGI:3687865 Jiang YH, Armstrong D, Albrecht U, Atkins CM, Noebels JL, Eichele G , Sweatt JD , Beaudet AL, Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. Neuron. 1998 Oct;21(4):799-811

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