Slco1c1-2A-CreERT2

Mfr.No.	NM-KI-200262
Description	Model Description: 2A-CreERT2 expression cassette was knocked into the Slco1c1 gene stop codon site. Slco1c1 encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. When Slco1c1-2A-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLCO1C1 positive cells. Official Symbol: Slco1c1 NCBI ID link: 58807 MGI ID link: 1889679 Ensembl ID link: ENSMUSG00000030235 Pubmed link: Slco1c1 Human Ortholog: SLCO1C1
Nomenclature	C57BL/6JSmoc-Slco1c1^{em1(2A-CreERT2)Smoc}
Strain	Repository Live
KI/KO Gene	Slco1c1
Synonyms	Oatp2, Oatpf, OATP-F, OATP-14, Slc21a14

Applications Range	Ischemic infarction
Research Application	Cre/Dre-Driver

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