R26-CAG-LSL-hEGFR*T790M/del19-Luc-tdTomato-BHAM00269

Mfr.No.	NM-KI-190009
Description	Model Description: A SA-2xpolyA-CAG-LSL-EGFR(T790M-del19)-IRES-luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EGFR(T790M-del19) protein. Official Symbol: Gt(ROSA)26Sor NCBI ID: 14910 MGI ID: 104735 Ensembl ID: ENSMUSG00000086429 Pubmed: Gt(ROSA)26Sor Human Ortholog: On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Nomenclature	C57BL/6JSmoc-Gt(ROSA)26Sor^{em1(SA-2xpolyA-CAG-LSL-EGFR T790M-del19-luciferase-tdTomato)Smoc}
Application	Cancer
KI/KO Gene	Gt(ROSA)26Sor
Synonyms	R26,ROSA26,AV258896,Gtrgeo26,Gtrosa26,Thumpd3as1

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R26-CAG-LSL-hEGFR*T790M/del19-Luc-tdTomato