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Mc3r-KO

SKU : BHAM00175

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-190652
Description	Model Description: Exon 1 of Mc3r gene was deleted to generate Mc3r knockout mice. Official Symbol: Mc3r NCBI ID: 17201 MGI ID: 96929 Ensembl ID: ENSMUSG00000038537 Pubmed: Mc3r Human Ortholog: MC3R
Nomenclature	C57BL/6JSmoc-Mc3R^em1Smoc
Exon	Exon 1
Application	Obesity
Disease	Obesity
Disease	Cardio-metabolic Disease
KI/KO Gene	Mc3r
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Mc4r-KO(2)(NM-KO-205021) mice.
Synonyms	MC3-R

Reference	MGI:3579026 Chen AS, Marsh DJ, Trumbauer ME, Frazier EG, Guan XM, Yu H, Rosenblum CI, Vongs A, Feng Y, Cao L, Metzger JM, Strack AM, Camacho RE, Mellin TN, Nunes CN, Min W, Fisher J, Gopal-Truter S, MacIntyre DE, Chen HY, Van Der Ploeg LH, Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass. Nat Genet. 2000 Sep;26(1):97-102

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