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Ldlr-KO(2)

SKU : BHAM00170

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-210198
Description	Model Description: Ldlr-KO(2) mice(Stock No.NM-KO-210198) carry a knockout allele derived from the targeted deletion of exon 4. While Ldlr-KO mice(Stock No.NM-KO-190559) carrying the exon 6-10 deletion. Official Symbol: Ldlr NCBI ID: 16835 MGI ID: 96765 Ensembl ID: ENSMUSG00000032193 Pubmed: Ldlr Human Ortholog: LDLR
Nomenclature	C57BL/6JSmoc-Ldlr^em1Smoc
Exon	Exon 4.
Disease	familial hypercholesterolemia
Disease	Cardio-metabolic Disease
KI/KO Gene	Ldlr
Synonyms	Hlb301

Reference	MGI:4429407 Jones C, Hammer RE, Li WP, Cohen JC, Hobbs HH, Herz J, Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia. J Biol Chem. 2003 Aug 1;278(31):29024-30

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