Rabbit Anti-Human AKT3 Polyclonal

Mfr.No.	SPC-1102, SPC-1102D, SPC-1102D-A390, SPC-1102D-A488, SPC-1102D-A594, SPC-1102D-BI, SPC-1102D-FITC
Immunogen Species	Human
Alternative Names	Akt3 antibody, AKT3 kinase antibody, AKT3_HUMAN antibody, PKB gamma antibody, PKBG antibody, PRKBG antibody, Protein kinase Akt-3 antibody, Protein kinase B gamma antibody, RAC gamma antibody, RAC gamma serine/threonine protein kinase antibody, RACPK Gamma antibody, Serine threonine protein kinase Akt 3 antibody, STK 2 antibody, STK-2 antibody, STK2 antibody, V akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) antibody
Categories	Antibodies
Cellular Localization	Cytoplasm, Membrane
Certificate Of Analysis	A 1:250 dilution of SPC-1102 was sufficient for detection of AKT3 in 10 ug of human A549 cell line lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human AKT3 Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide of human Akt3 (AA402-416), Homo Sapiens (Human)
Immunogen Region	Synthetic peptide of human Akt3 (AA402-416)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Human
Tissue Specificity	In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.

Swissprot	Q9Y243
Accession Number	NP_005456
Gene Id	10000
Target	AKT3
Research Area	Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases, PKB / AKT, Cancer, Cell Cycle, PI3k/AKT Pathway

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.
Scientific Background	AKT3 is Ser/Thr Kinase that is activated by PIP2 produced by PI3K, leading to translocation of AKT3 to the plasma membrane where it can be activated by S/T phosphorylation by PDK1/2. It is a regulator of cell signalling events such as proliferation, differentiation, apoptosis, tumourigenesis and also plays a role in brain development and in glucose metabolism, in response to insulin and a variety of growth factors such as PDGF and IGF-1. It is upregulated in a number of cancers.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 55.775 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11914652-1	SPC-1102D	Unconjugated	100 ul	$331	Add to Cart
BHA11914652-2	SPC-1102D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11914652-3	SPC-1102D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11914652-4	SPC-1102D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11914652-5	SPC-1102D-BI	Biotin	100 ul	$380	Add to Cart
BHA11914652-6	SPC-1102D-FITC	FITC	100 ul	$375	Add to Cart

AKT3 Antibody - SPC-1102

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