Integrated AAV Offerings: From Cutting-Edge Products to Advanced Custom Services
Overcoming AAV Technology Challenges with Expertly Tailored Vector Design and Production
AAV Plasmid Vectors
AAV plasmids are essential components in the production of Adeno-Associated Virus (AAV) vectors. Traditional transient transfection method involves co-transfecting HEK293 cells with three plasmids containing the necessary cis and trans components for AAV replication and propagation: pAAV, pRep-Cap, pHelper.
In collaboration with AAVnerGene, we offer AAV plasmids designed for different production systems, including AAVone, AAVdual, and AAVtri. Each system is tailored to meet specific vector design and production needs, providing flexibility and scalability in AAV production. These systems are optimized to enhance the efficiency and yield of AAV vector production, accommodating various research and therapeutic applications.
AAV Plasmids by Production System
Production System | Plasmid Backbone | Examples | Ad Genes | Rep/Cap | Genome |
AAVone System | pAAVone | pAAVone-AAV9-CMV-EGFP | Yes | Yes | ssAAV |
pAAVone-sc | pAAVone-sc-AAV9-CMV-EGFP | Yes | Yes | scAAV | |
AAVdual System | pAAVdual | pAAVdual-CMV-EGFP | Yes | No | ssAAV |
pAAVdual-sc | pAAVdual-sc-CMV-EGFP | Yes | No | scAAV | |
AAVtri System | pAAVtri | pAAVtri-CMV-EGFP | No | No | ssAAV |
pAAVtri-sc | pAAVtri-sc-CMV-EGFP | No | No | scAAV | |
Ad helper | mini-pHelper | Yes | No | No |
AAV Services
AAV Vector Design & Cloning
Expert consultation, design, gene synthesis, and cloning of custom AAV vectors tailored to your research needs.
Learn moreAAV Packaging Service
Reliable, affordable, and fully customizable AAV packaging service with diverse serotype options and high titer.
Learn moreAAV QC & Characterization
Comprehensive quality control assays including qPCR, SDS-PAGE, mass photometry, and next-generation sequencing.
Learn moreOther Viruses at Biohippo
Neural Circuit Tracing
Biohippo offers a variety of viral vectors, including RV, HSV, PRV, and VSV, to replace conventional tracers with the highly efficient, more specific, and less invasive viral method.
Learn MoreLentivirus
Biohippo offers TF reporter lentivirus, immunotherapy lentivirus, validated shRNA, cDNA, and miRNA lentiviruses to meet diverse research needs. We also offer customized service at affodable price.
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