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Integrated AAV Offerings: From Cutting-Edge Products to Advanced Custom Services
Overcoming AAV Technology Challenges with Expertly Tailored Vector Design and Production
AAV Plasmids for Production
AAV plasmids are essential components in the production of Adeno-Associated Virus (AAV) vectors, serving as the foundation for high-efficiency gene delivery in research and therapeutic applications.
In collaboration with AAVnerGene, we offer a comprehensive range of AAV plasmids designed for different production systems, including AAVone, AAVdual, and AAVtri. Each system is tailored to meet specific vector design and production needs, providing flexibility and scalability in AAV production. The AAVone system utilizes pAAVone and pAAVone-sc plasmids, while the AAVdual system employs pAAVdual and pAAVdual-sc plasmids. For more advanced applications, the AAVtri system includes pAAVtri, pAAVtri-sc, and mini-pHelper plasmids. These systems are optimized to enhance the efficiency and yield of AAV vector production, accommodating various research and therapeutic applications.
AAV Plasmids List
| Production System | Plasmid Backbone | Examples | Ad Genes | Rep/Cap | Genome |
| AAVone System | pAAVone | pAAVone-AAV9-CMV-EGFP | Yes | Yes | ssAAV |
| pAAVone-sc | pAAVone-sc-AAV9-CMV-EGFP | Yes | Yes | scAAV | |
| AAVdual System | pAAVdual | pAAVdual-CMV-EGFP | Yes | No | ssAAV |
| pAAVdual-sc | pAAVdual-sc-CMV-EGFP | Yes | No | scAAV | |
| AAVtri System | pAAVtri | pAAVtri-CMV-EGFP | No | No | ssAAV |
| pAAVtri-sc | pAAVtri-sc-CMV-EGFP | No | No | scAAV | |
| Ad helper | mini-pHelper | Yes | No | No |
AAV Services
Custom AAV Vector Design and Cloning
Expert consultation and design of custom AAV vectors tailored to your research needs.
AAV Production Services
Scalable production services from small pilot batches to large-scale bioreactor production.
AAV Purification Services
High-quality purification using state-of-the-art techniques like affinity chromatography.
AAV Quality Control and Characterization
Comprehensive quality control assays including qPCR, SDS-PAGE, and next-generation sequencing.
Preclinical Development Services
In vitro and in vivo studies to evaluate transduction efficiency, tissue tropism, and safety.
Ready-to-Use AAV Vectors
Off-the-shelf AAV vectors for standard applications and proof-of-concept studies.
Learn About Available Viruses at Biohippo
Neural Circuit Tracing
Biohippo offers a variety of viral vectors, including RV, HSV, PRV, and VSV, to replace conventional tracers with the highly efficient, more specific, and less invasive viral method.
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