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Integrated AAV Offerings: From Cutting-Edge Products to Advanced Custom Services
Overcoming AAV Technology Challenges with Expertly Tailored Vector Design and Production
AAV Characterization
With a robust academic and industry background in AAV gene therapy, the AAVnerGene team excels in establishing a reliable platform for AAV characterization and analysis. Our services extend beyond standard quality control tests such as genomic titer, purity analysis, toxicity testing, and endotoxin or mycoplasma level assessment. We also offer advanced evaluations including vector genome identity, ITR integrity, DNA impurities, empty/full ratios, and a variety of comprehensive analyses. These services are designed to meet the specific needs of our valued clients.
QC Services We Offer
| QC | Method | Turnaround | Price | Sample Requirement |
| Genome Titration | qPCR | 1-2 day | $50/sample (Free in AAV Packaging Services) |
*Primer/probe sequences; ~20μl of samples |
| Genome Titration | ddPCR/dPCR | 3-5 day | $200/sample | *Primer/probe sequences; ~20μl of samples |
| Capsid Titration | ELISA | 3-5 day | $400/sample | *Serotypes and buffers; ~20μl of samples |
| Purity Analysis | SDS-PAGE | 3-5 day | $200/sample | ~20μl of sample with titer >1E+12vg/ml |
| Full/Empty Ratio | AUC | 3-5 day | $2,000/sample | ~400μl of sample with titer >1E+12vg/ml |
| Full/Empty Ratio | Mass Photometry | 1-2 day | $800/sample | 20μl of sample with titer >5+11vg/ml |
| Endotoxin | LAL assay | 3-5 day | $200/sample | ~20μl of samples |
| Endotoxin Removal | Resin-PMB | 3-5 day | $200/sample | ~20μl of samples |
| Bioburden Testing | Direct plating | 3-5 day | $200/sample | ~20μl of samples |
| Mycoplasma Testing | PCR | 3-5 day | $200/sample | ~20μl of samples |
| Vector Genome Identity | TapeStation | 1-2 day | $200/sample | ~100μl of sample with titer >1E+12vg/ml |
| Vector Genome Identity | PacBio Seq | 4 weeks | Request | ~100μl of sample with titer >1E+12vg/ml |
| DNA Impurity | PacBio Seq | 4 weeks | Request | ~100μl of sample with titer >1E+12vg/ml |
| DNA Impurity | qPCR | 3-5 day | 200/Target | ~20μl of samples |
Contact US for QC Services
Contact our technical team today to discuss your project requirements.
AAV Services
Custom AAV Vector Design and Cloning
Expert consultation and design of custom AAV vectors tailored to your research needs.
AAV Production Services
Scalable production services from small pilot batches to large-scale bioreactor production.
AAV Purification Services
High-quality purification using state-of-the-art techniques like affinity chromatography.
AAV Quality Control and Characterization
Comprehensive quality control assays including qPCR, SDS-PAGE, and next-generation sequencing.
Preclinical Development Services
In vitro and in vivo studies to evaluate transduction efficiency, tissue tropism, and safety.
Ready-to-Use AAV Vectors
Off-the-shelf AAV vectors for standard applications and proof-of-concept studies.
Learn About Available Viruses at Biohippo
Neural Circuit Tracing
Biohippo offers a variety of viral vectors, including RV, HSV, PRV, and VSV, to replace conventional tracers with the highly efficient, more specific, and less invasive viral method.
Learn More