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Home / Antibodies

14-3-3 sigma Antibody (N1084)

SKU : BHA17103537

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NSJ Bioreagents

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Mfr.No.	N1084, N1084-25UG, N1084-100UG
Clonality	Polyclonal
Description	14-3-3 proteins are regulators of a diverse group of signaling proteins, including kinases, phosphatases, and transmembrane receptors, and have roles in a wide range of physiological processes including transcription, intracellular signaling, cell cycle control and apoptosis. There are seven 14-3-3 proteins in most mammals: beta, gamma epsilon, zeta, eta, sigma and tau. 14-3-3 sigma, also called Stratifin, is a product of the SFN gene. It is a tumor suppressor gene inactivated via DNA methylation. Reduced or no expression of 14-3-3 sigma is seen in various carcinoma including skin, breast and prostate, suggesting that 14-3-3 gene silencing may be involved in tumor progression.
Formulation	0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Rabbit
Immunogen Region	A recombinant protein fragment from the internal region of 14-3-3 sigma was used as the immunogen for this antibody. The amino acid sequence is common to the ~30kDa and ~20kDa isoforms.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Gene Id	2810

Buffer	1X PBS, pH 7.4
Concentration	0.5 mg/ml
Format	Purified
Purification	Protein A affinity chromatography
Storage	Aliquot the 14-3-3 sigma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB
Dilution	Western blot: 1-3ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17103537-1	N1084-25UG	25ug	$209		Add to Cart
BHA17103537-2	N1084-100UG	100ug	$419		Add to Cart

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