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Home / Antibodies

14-3-3 epsilon Antibody / YWHAE (V7362SAF)

SKU : BHA17126367

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NSJ Bioreagents

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Mfr.No.	V7362SAF-100UG
Clonality	Monoclonal (mouse origin)
Description	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3 epsilon has also been identified as a possible susceptibility gene for schizophrenia.
Formulation	1 mg/ml in 1X PBS; BSA free, sodium azide free
Host	Mouse
Immunogen Region	Full length recombinant human protein was used as the immunogen for the 14-3-3 epsilon antibody.
Isotype	Mouse IgG2a, kappa
Species Reactivity	Human
Note	The stated application concentrations are suggested starting points. Titration of the 14-3-3 epsilon antibody may be required due to differences in protocols and secondary/substrate sensitivity.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Uniprot	P62258

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the 14-3-3 epsilon antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	WB, IHC-P
Description	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT

Product Manual	<a href="https://www.nsjbio.com/tds-pdf/14-3-3-epsilon-antibody-cptc-ywhae-1-protein-microarray-validated-v7362" target="_blank">Datasheet</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA17126367	V7362SAF-100UG	100 ug	$499		Add to Cart

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