Lentivirus

Lentiviruses (LVs), a subgroup of the retrovirus family, are single-stranded RNA viruses notable for their ability to integrate into the host genome in both dividing and non-dividing cells. This integration facilitates long-term expression in a wide range of cell types, both in vitro and in vivo. LVs are extensively used in gene therapy and research due to their versatility and efficiency in delivering genetic material into cells. Their application spans from correcting genetic defects to exploring gene functions, making them a vital tool in biomedical research and therapeutic development.