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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTSLP(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Tslptm(hT
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Tslp
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pAtp4b-hCLDN18.2-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Tumor Targets
- KI/KO Gene : Tslp
-
pAlb-hLPA-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Repository Live
- Target : Metabolic Targe
- KI/KO Gene : LPA
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Rag2/IL2rg-KO/hKDR
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Repository Live
- Target : Metabolic Targe
- KI/KO Gene : IL2RG
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R26-LSL-hIL4(M-NSG)
- Description : Model Descripti
- Nomenclature : NOD-PrkdcscidIl
- Strain : Developing
- Target : Metabolic Targe
- KI/KO Gene : Gt(ROSA)26Sor
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hTNFSF15(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Metabolic Targe
- KI/KO Gene : Tnfsf15
-
hTSLP/hIL17RA
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ts
- Strain : Embryo cryopres
- Target : Cytokines
- KI/KO Gene : TSLP
-
R26-LSL-hIL15-Flag-IRES-EGFP
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Gt
- Strain : Repository Live
- Target : Cytokines
- KI/KO Gene : Gt(ROSA)26Sor
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hIL3/hCSF2(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Il3tm(hIL
- Strain : Repository Live
- Target : Cytokines
- KI/KO Gene : Gt(ROSA)26Sor
-
hIL5/hIL5RA(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Il5tm(hIL
- Strain : Repository Live
- Target : Cytokines
- KI/KO Gene : Gt(ROSA)26Sor
-
hLILRB1-hLILRB2-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Tumor Targets
- KI/KO Gene : Gt(ROSA)26Sor
-
hCTLA-4/hCD28(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ct
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : CD28
-
hGFRAL(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Gf
- Strain : Developing
- Target : Tumor Targets
- KI/KO Gene : Gfral
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