DENARASE^® - Enzyme Characteristics

Cofactor Requirements DENARASE® necessitates magnesium ions (Mg2+) as a cofactor to facilitate its enzymatic activity. The enzyme's optimal performance is attained with a concentration of 1-2 mM of Mg2+ ions. It is important to note that an excessive amount of MgCl2 can diminish the enzyme's effectiveness.

Stability and Optimal Storage The enzyme maintains its stability and activity when stored at -20 °C, with a guaranteed shelf life of at least 24 months post-manufacture. Storing DENARASE® below -70 °C is discouraged as it leads to a reduction in enzymatic activity.

Packaging and Shipping DENARASE® is packaged in vials that meet the non-pyrogenic, USP Class VI standards, ensuring safety and compatibility. These vials are then secured in polystyrene containers for protection during transportation, which is conducted under cooled conditions. It is crucial to differentiate between shipping and storage temperatures, as variations during transit do not compromise the product's integrity.

Enhanced Availability in the US Market R&D-grade DENARASE® is now readily available in the US market through Biohippo Inc, a local distributor based in Gaithersburg, Maryland. This new availability streamlines procurement, offering expedited delivery and eliminating the complexities of customs clearance, thus ensuring seamless access for research and development endeavors.