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Anti-EPHB4 Antibody BHA11301103
Alternative: Ephrin type-B receptor 4|Hepatoma transmembrane kinase|Tyrosine-protein kinase TYRO11|EPHB4|HTK|MYK1|TYRO11
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 7q22.1
Immunogen: Synthetic peptide, corresponding to amino acids 580-630 of Human EphB4.
Description: EphB4, also known as Htk, Myk1, Tyro11, and Mdk2, is a member of the Eph receptor family, which binds of the ephrin ligand family. Two classes of receptors exist, designated A and B, that have an extracellular domain made up of a globular domain, a cysteine-rich domain, and two fibronectin type III domains, followed by the transmembrane region and cytoplasmic region. The cytoplasmic region contains juxtamembrane motif with two tyrosines, which are the major autophosphorylation sites, along with a kinase domain, and a conserved sterile alpha motif (SAM) in the carboxyl terminus, which includes one conserved tyrosine. Ligand recognition and binding leads to activation of intrinsic kinase activity.
TARGETWeight: 108 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: EphB4 (E601) polyclonal antibody detects endogenous levels of EphB4 protein.
Description: Western blot (WB) analysis of EphB4 (E601)pAb at 1:500 dillutionLane1:Hcc827 whole cell lysateLane2:LO2 whole cell lysateLane3:The Kidney tissue lysate of MouseLane4:The Kidney tissue lysate of Rat
Description: Immunohistochemistry (IHC) analyzes of EphB4 (E601) pAb in paraffin-embedded human brain tissue.