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Anti-NFYB Antibody BHA11301054
Alternative: Nuclear transcription factor Y subunit beta|CAAT box DNA-binding protein subunit B|Nuclear transcription factor Y subunit B|NF-YB|NFYB|HAP3
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 12q23.3
Immunogen: Synthetic peptide, corresponding to the N-terminal of Human NF-YB.
Description: The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed
for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein, histone-fold “handshake” motif in a manner analogous to the histone proteins H2B and H2A, respectively.
TARGETWeight: 32 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Specificity: NF-YB (Q30) polyclonal antibody detects endogenous levels of NF-YB protein.
Description: Immunohistochemistry (IHC) analyzes of NF-YB (Q30) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.