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Anti-EPCAM Antibody BHA11301027
Alternative: Epithelial cell adhesion molecule|Ep-CAM|Adenocarcinoma-associated antigen|Cell surface glycoprotein Trop-1|Epithelial cell surface antigen|Epithelial glycoprotein|EGP|Epithelial glycoprotein 314|EGP314|hEGP314|KS 1/4 antigen|KSA|Major gastrointestinal tumor-associated protein GA733-2|Tumor-associated calcium signal transducer 1|CD326|EPCAM|GA733-2|M1S2|M4S1|MIC18|TACSTD1|TROP1
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 2p21
Immunogen: Synthetic peptide, corresponding to amino acids 120-170 of Human EPCAM.
Description: The epithelial cell adhesion molecule Ep-CAM, which is also design atedtumor-associated calcium signal transducer 1 and MK-1, is a monomeric membrane glycoprotein that is expressed in most normal human epithelium and in most carcinomas. The human Ep-CAM gene encodes a 314 amino acid protein that is expressed as two forms, a 40 kDa major form and a 42 kDa minor form, which are reduced to 35 kDa upon treatment with the aminoglycosylation inhibitor tunicamycin. Ep-CAM is overexpressed in a variety of carcinomas and is, therefore, a potential target for the visualization and therapy of human solid tumours. Ep-CAM contains an extracellular domain containing two epidermal growth factor-like repeats, followed by a cysteinepoor region, which are necessary for the adhesion properties of the molecule.
TARGETWeight: 40 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: EPCAM (H150) polyclonal antibody detects endogenous levels of EPCAM protein.