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Anti-DLGAP1 Antibody BHA11300968
Alternative: Disks large-associated protein 1|DAP-1|Guanylate kinase-associated protein|hGKAP|PSD-95/SAP90-binding protein 1|SAP90/PSD-95-associated protein 1|SAPAP1|DLGAP1|DAP1|GKAP
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: primary antibodies|polyclonal antibodies
Chromosome Location: 18p11.31
Immunogen: Synthetic peptide, corresponding to amino acids 791-840 of Human SAPAP1.
Description: Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membraneassociated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-α, DAP-1-β, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP1, through the guanylate kinase domain. SAPAP1 is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. N-terminal splice variants of SAPAP1 are expressed as 95 and 130 kDa proteins. SAPAP1 is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.
TARGETWeight: 108 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: SAPAP1 (E817) polyclonal antibody detects endogenous levels of SAPAP1 protein.
Description: Western blot (WB) analysis of SAPAP1 (E817) polyclonal antibody at 1:500 dilutionLane1:The Brain tissue lysate of Mouse(40ug)Lane2:The Brain tissue lysate of Rat(40ug)Lane3:U-87MG whole cell lysate(40ug)Lane4:U-251MG whole cell lysate(40ug)
Description: Immunohistochemistry (IHC) analyzes of SAPAP1 (E817) pAb in paraffin-embedded human brain carcinoma tissue at 1:50.