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Anti-FOXO4 Antibody BHA11300950
Alternative: Forkhead box protein O4|Fork head domain transcription factor AFX1|AFX|AFX1|MLLT7|FOXO4
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: Xq13.1
Immunogen: Synthetic peptide, corresponding to amino acids 418-465 of Human FoxO4.
Description: FOX4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.
TARGETWeight: 65 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: FoxO4 (K447) polyclonal antibody detects endogenous levels of FoxO4 protein.
Description: Western blot (WB) analysis of FoxO4 (K447) pAb at 1:500 dilutionLane1:HEK293T whole cell lysate(40ug)Lane2:Hela whole cell lysate(40ug)Lane3:K562 whole cell lysate(40ug)Lane4:PC12 whole cell lysate(40ug)Lane5:3T3-L1 whole cell lysate(40ug)