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Anti-DAPP1 Antibody BHA11300918
Alternative: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide|hDAPP1|B lymphocyte adapter protein Bam32|B-cell adapter molecule of 32 kDa|HSPC066|BAM32|DAPP1
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 4q23
Immunogen: Synthetic peptide, corresponding to amino acids 102-150 of Human DAPP1.
Description: B cell adapter molecule (BAM32) is also designated a dual adapter for phosphotyrosine and 3-phosphotyrosine, and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC γ2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation. BAM32, which contains one PH domain and one SH2 domain, is primarily expressed in placenta and lung tissues, but can also be detected in heart, liver, pancreas and brain.
TARGETWeight: 32 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: DAPP1 (E135) polyclonal antibody detects endogenous levels of DAPP1 protein.
Description: Immunohistochemistry (IHC) analyzes of DAPP1 (E135) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.