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Home / Primary Antibodies / IHC Antibodies

Anti-VDR Antibody BHA11300902

SKU : BHA11300902

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Mfr.No.	BS1774
Alternative Names	Vitamin D3 receptor ; VDR ; 1,25-dihydroxyvitamin D3 receptor ; Nuclear receptor subfamily 1 group I member 1 ; NR1I1
Antigen	VDR
Categories	Primary Antibodies
Chromosome Location	12q13.11
Clonality	polyclonal
Description	The vitamin D receptor (VDR), also known as the calcitriol receptor, and also known as NR1I1 (nuclear receptor subfamily 1, group I, member 1), is a member of the nuclear receptor family of transcription factors. Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or trans-repression of specific gene products.It is an intracellular hormone receptor that specifically binds 1,25(OH)2D3 and mediates its effects. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 161-210 of Human VDR.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P11473
Uniprot	P11473
Weight	43, 55 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: VDR (N204) polyclonal antibody detects endogenous levels of VDR protein
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300902	BS1774	50µl	$190.44		Add to Cart
BHA11300902	BS1774	100µl	$294.44		Add to Cart

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