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Anti-Mtatp6 Antibody BHA11300829
Alternative: ATP synthase subunit a|F-ATPase protein 6|Mtatp6|Atp6|Atpase6|mt-Atp6
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: primary antibodies|polyclonal antibodies
Immunogen: A synthetic peptide corresponding to amino acids 55-70 of Mouse ATP6.
Description: ATP6, also known as MT-ATP6, ATPASE6 or MTATP6, is a 226 amino acidmulti-passmembrane protein that localizestomitochondria and functions as a component of the F0 proton channel, playing a direct role in the transport of protons acrossthe mitochondrial membrane. Defectsin the gene encoding ATP6 are the cause of infantile bilateralstriatal necrosis, Leigh syndrome (LS),Leber hereditary optic neuropathy(LHON) and neurogenic muscle weakness, ataxia, and retinitis pigmentosa (NARP), all of which are neurological or retinal disorders. The gene encoding ATP6 exists as part of themitochondrial genome.
TARGETWeight: 25 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.Specificity: ATP6 polyclonal antibody detects endogenous levels of ATP6 protein.
Description: Western blot (WB) analysis of ATP6 polyclonal antibody at 1:1000 dilutionLane1:The muscle tissue lysate of Rat (47μg)Lane2:The muscle tissue lysate of Mouse(37μg)