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Anti-EFNB1 Antibody BHA11300791
Alternative: Ephrin B1|EphrinB1|EFL-3|ELK ligand|ELK-L|EPH-related receptor tyrosine kinase ligand 2|LERK-2|EFNB1|EFL3|EPLG2|LERK2
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: Xq13.1
Immunogen: Synthetic peptide, corresponding to amino acids 280-330 of Human Ephrin-B1.
Description: Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.
TARGETWeight: 38, 45 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: Ephrin-B1 (N312) polyclonal antibody detects endogenous levels of Ephrin-B1 protein.
Description: Western blot (WB) analysis of Ephrin-B1 (N312) polyclonal antibody at 1:500 dilutionLane1:Hela whole cell lysateLane2:Raw264.7 whole cell lysateLane3:PC12 whole cell lysate