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Anti-PRKDC Antibody BHA11300786
Alternative: DNA-dependent protein kinase catalytic subunit|DNA-PK catalytic subunit|DNA-PKcs|DNPK1|p460|PRKDC|HYRC|HYRC1
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 8q11.21
Immunogen: Synthetic peptide, corresponding to amino acids 2022-2070 of Human DNA-PK.
Description: The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy termini that is not present in the PI 3- and PI 4-kinases. All of the members of the PIK-related kinases are also over 270 kDa. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiectases) in the conjunctivae of the eyes.
TARGETWeight: 450 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: DNA-PK (Y2052) polyclonal antibody detects endogenous levels of DNA-PK protein.
Description: Immunohistochemistry (IHC) analyzes of DNA-PK (Y2052) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.