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Anti-PLCG2 Antibody BHA11300739
Alternative: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2|Phosphoinositide phospholipase C-gamma-2|Phospholipase C-IV|PLC-IV|Phospholipase C-gamma-2|PLC-gamma-2|PLCG2|PLCγ2|PLC-γ2|PLC γ-2
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 16q24.1
Immunogen: Synthetic peptide, corresponding to amino acids 1180-1230 of Human PLC γ2.
Description: Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. There are many mammalian PLC isozymes, including PLC β1, PLC β2, PLC β3, PLC β4, PLCγ1, PLCγ2, PLC δ1, PLC δ2 and PLCe. PLCδ exists as four different isoforms. PLC δ1, a calcium signal amplifier, is activated by an atypical GTP-binding protein. In addition, PLC δ1 is an effector for GTP-binding protein transglutaminase II-mediated oxytocin receptor and α1B-adrenoreceptor signaling. Mouse PLC δ1 is highly expressed in brain, heart, lung and testis.
TARGETWeight: 148 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: PLC γ2 (N1211) polyclonal antibody detects endogenous levels of PLC γ2 protein.
Description: Western blot (WB) analysis of PLC γ2 (N1211) polyclonal antibody at 1:500 dilutionLane1:Hela cell lysateLane2:sp2/0 cell lysateLane3:Rat lung tissue lysate
Description: Immunohistochemistry (IHC) analyzes of PLC γ2 (N1211) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.