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Anti-PECAM1 Antibody BHA11300729
Alternative: Platelet endothelial cell adhesion molecule|PECAM-1|EndoCAM|GPIIA'|PECA1|CD31|PECAM1
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 17q23.3
Immunogen: Synthetic peptide, corresponding to amino acids 670-720 of Human CD31.
Description: CD31 (Platelet Endothelial Cell Adhesion Molecule-1: PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells and endothelial cells, and modulates cell adhesion, endothelial cell migration and angiogenesis. CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical stress or oxidative stress), presumably by Src family members. The tyrosine phosphorylation mediates associations with a number of SH2 domain containing binding partners such as PI3-kinase, SHIP, PLCγ and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules.
TARGETWeight: 130 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: CD31/PECAM-1 (T709) polyclonal antibody detects endogenous levels of CD31 protein.
Description: Western blot (WB) analysis of CD31/PECAM-1 (T709) polyclonal antibody
Description: Immunohistochemistry (IHC) analyzes of CD31/PECAM-1 (T709) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.