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Anti-NFATC3 Antibody BHA11300716
Alternative: Nuclear factor of activated T-cells|cytoplasmic 3|NF-ATc3|NFATc3|NFATx|T-cell transcription factor NFAT4|NF-AT4|NFAT4|NFATC3
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 16q22.1
Immunogen: Synthetic peptide, corresponding to amino acids 130-180 of Human NFAT4.
Description: NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurindependent 4) is a member of the nuclear factors of activated T cells DNAbinding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components, a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.
TARGETWeight: 115 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: NFAT4 (E159) polyclonal antibody detects endogenous levels of NFAT4 protein.
Description: Western blot (WB) analysis of NFAT4 (E159) pAb at 1:500 dillutionLane1:PC3 whole cell lysate(60μg)Lane2:The Testis tissue lysate of Mouse(60μg)Lane3:The Testis tissue lysate of Rat(60μg)