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Anti-MYL12A/MYL9 Antibody BHA11300709
Alternative: Myosin regulatory light polypeptide 9|20 kDa myosin light chain|Short name=LC20|MLC-2C|Myosin RLC|Myosin regulatory light chain 2, smooth muscle isoform|Myosin regulatory light chain 9|Myosin regulatory light chain MRLC1|MLC2|MRLC1|MYRL2|Myosin regulatory light chain 12A|MLC-2B|Myosin RLC|Myosin regulatory light chain 2, nonsarcomeric|Myosin regulatory light chain MRLC3|MYL12A|MLCB|MRLC3|RLC
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Immunogen: Synthetic peptide, corresponding to the 10-40 of Human MYL9.
Description: Myosin regulatory light chains, including MRCL3 (also known as MRLC3 or MLCB), MRLC2 (also known as MLC-B) and MYL9 (also known as LC20, MLC2, MRLC1 or MYRL2), regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the Actin-activated myosin ATPase activity, thereby regulating the contractile activity. Myosin light chain is also located in striated skeletal muscle, where its function remains undefined.
TARGETWeight: 20 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: MYL9/MYL12A (P13) polyclonal antibody detects endogenous levels of MYL9 and MYL12A protein.
Description: Immunohistochemistry (IHC) analysis of MYL9/MYL12A (P13) pAb in paraffin-embedded human lung carcinoma tissue.