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Anti-EIF4G1 Antibody BHA11300691
Alternative: eIF-4-gamma 1|eIF-4G 1|eIF-4G1|p220|EIF4G1|1981|EIF4G1|600495|Q04637|DKFZp686A1451|EIF4F|EIF4G|p220
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: primary antibodies|polyclonal antibodies
Chromosome Location: 3q27.1
Immunogen: Synthetic peptide, corresponding to amino acids 1080-1130 of Human eIF4G.
Description: The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4G, eIF4E, and eIF4A. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E is a 25 kDa protein that binds to the mRNA “cap” during an early step in the initiation of protein synthesis. eIF4A acts as an ATP-dependent RNA helicase. eIF4G acts as a bridge between eIF4E, eIF4A, and the eIF3 complex.
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: eIF4G (Q1103) polyclonal antibody detects endogenous levels of eIF4G protein.
Description: Immunohistochemistry (IHC) analyzes of eIF4G (Q1103) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.