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Anti-CEBPE Antibody BHA11300674
Alternative: CCAAT/enhancer-binding protein epsilon|C/EBP epsilon|CEBPE|C/EBPε
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 14q11.2
Immunogen: Synthetic peptide, corresponding to amino acids 38-92 of Human C/EBP-ε.
Description: C/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP α uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic α helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP α appears to function exclusively in terminally-differentiated, growth-arrested cells. Additional family members include C/EBP β, C/EBP γ, C/EBP δ and C/EBP ε, all of which exhibit similar DNA-binding specificities and affinities to C/EBP α. Furthermore, C/EBP β and C/EBP δ readily form heterodimers both with each other as well as with C/EBP α.
TARGETWeight: 30, 45 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: C/EBP-ε (K70) polyclonal antibody detects endogenous levels of C/EBP-ε protein.
Description: Immunohistochemistry (IHC) analyzes of C/EBP-ε (K70) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.