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Anti-XRCC6 Antibody BHA11300659
Alternative: X-ray repair cross-complementing protein 6|5'-deoxyribose-5-phosphate lyase Ku70|5'-dRP lyase Ku70|70 kDa subunit of Ku antigen|ATP-dependent DNA helicase 2 subunit 1|ATP-dependent DNA helicase II 70 kDa subunit|CTC box-binding factor 75 kDa subunit|CTC75|CTCBF|DNA repair protein XRCC6|Lupus Ku autoantigen protein p70|Ku70|Thyroid-lupus autoantigen|TLAA|X-ray repair complementing defective repair in|Chinese hamster cells 6|XRCC6|G22P1
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 22q13.2
Immunogen: Synthetic peptide, corresponding to amino acids 560-600 of Human Ku-70.
Description: The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 (or p86), which is also known by the synonym Ku-80 (or p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation.
TARGETWeight: 70 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.Specificity: Ku-70 (R586) polyclonal antibody detects endogenous levels of Ku-70 protein
Description: Immunohistochemistry (IHC) analyzes of Ku-70 (R586) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.