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Anti-TUBG1 Antibody BHA11300645
Alternative: Tubulin gamma-1 chain|Gamma-1-tubulin|Gamma-tubulin complex component 1|GCP-1|TUBG1|TUBG|Tubulin γ1|Tubulin-γ1|Tubulinγ1
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 17q21.31
Immunogen: Synthetic peptide, corresponding to amino acids 380-430 of Human Tubulin γ.
Description: TUB4, the gene for Saccharomyces cerevisiae γ-Tubulin, encodes a 473 amino acid structural protein that localizes to the spindle pole body. γ Tubulin, an essential protein for cell growth, organizes microtubule arrays in the nucleus and cytoplasm. γ Tubulin-depleted cells fail to form functional spindles and arrest during nuclear division. γ Tubulin associates with spindle body components Spc97 and Spc98 to form the γ Tubulin complex. The budding yeast γ Tubulin complex contains one molecule each of Spc97 and Spc98 and two molecules of γ Tubulin. In the SPB, Spc110 binds Spc97 and Spc98 of the γ Tubulin complex. 2D gel analysis indicates five isoforms of γ Tubulin. The phosphorylation of γ Tubulin at Tyr 445 plays a regulatory role in microtubule formation. The incidence rate for this phosphorylation event peaks during G1.
TARGETWeight: 51 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.Specificity: Tubulin γ (F414) polyclonal antibody detects endogenous levels of Tubulin γ protein.
Description: Immunohistochemistry (IHC) analyzes of Tubulin γ (F414) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.