ebiohippo is a top distributor of the best and most reliable ELISA and Assay kits. We can provide a wide range of kits from well-known suppliers and brands with authentic and validated data. We provide antibodies to help you quickly identify and quantify proteins, and evaluate other necessary data for various applications in life sciences.
Anti-GSK3B/GSK3A Antibody BHA11300573
Alternative: Glycogen synthase kinase-3 alpha|GSK-3 alpha|GSK3A|Glycogen synthase kinase-3 beta|GSK-3 beta|GSK3B
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: primary antibodies|polyclonal antibodies
Immunogen: Synthetic peptide, corresponding to amino acids 250-300 of Human GSK3α.
Description: Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily; GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.
TARGETWeight: 46, 51 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: GSK3α/β (G273) polyclonal antibody detects endogenous levels of GSK3α/β protein.
Description: Western blot (WB) analysis of GSK3α/β (G273) polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate(40ug)Lane2:A549 whole cell lysate(40ug)Lane3:CT26 whole cell lysate(40ug)Lane4:C6 whole cell lysate(40ug)Lane5:The Heart tissue lysate of Rat(10ug)
Description: Immunohistochemistry (IHC) analyzes of GSK3α/β (G273) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
Description: Western blot (WB) analysis of GSK3α/β (G273) pAb at 1:500 dilutionLane1:The lung tissue lysate of Rat(40ug)Lane2:HEK293T whole cell lysate(30ug)Lane3:A549 whole cell lysate(30ug)Lane4:The lung tissue lysate of Mouse(40ug)Lane5:The heart tissue lysate of Rat(15ug)