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Anti-KDR Antibody BHA11300534
Alternative: Vascular endothelial growth factor receptor 2|VEGFR-2|Fetal liver kinase 1|FLK-1|Kinase insert domain receptor|Protein-tyrosine kinase receptor flk-1|CD309|KDR|FLK1|VEGFR2
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 4q12
Immunogen: Synthetic peptide, corresponding to amino acids 1150-1200 of Human VEGFR2.
Description: Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulinlike sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
TARGETWeight: 150, 210 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: VEGFR2 (Q1169) polyclonal antibody detects endogenous levels of VEGFR2 protein.
Description: Immunohistochemistry (IHC) analyzes of VEGFR2/Flk-1 (Q1169) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.