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Anti-TIMP2 Antibody BHA11300529
Alternative: Metalloproteinase inhibitor 2|CSC-21K|Tissue inhibitor of metalloproteinases 2|TIMP-2|TIMP2
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 17q25.3
Immunogen: Synthetic peptide, corresponding to amino acids 10-60 of Human TIMP-2.
Description: TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases 1, 2, 3 and 4) complex with metalloproteinases such as collagenases, gelatin-ases and stromelysins, resulting in irreversible inactivation of the metallopro-teinase. TIMP-1 has been found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus and remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart, with low levels expressed in liver, brain, lung, thymus and spleen.
TARGETWeight: 24 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: TIMP2 (A47) polyclonal antibody detects endogenous levels of TIMP2 protein.
Description: Western blot (WB) analysis of TIMP2 (A47) polyclonal antibody at 1:500 dilutionLane1:Hela whole cell lysate(40ug)Lane2:HEK293T whole cell lysate(40ug)Lane3:The lung tissue lysate of Mouse(40ug)Lane4:The lung tissue lysate of Rat(40ug)Lane5:The placenta tissue lysate of Rat(40ug)