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Anti-SRC Antibody BHA11300494
Alternative: Proto-oncogene tyrosine-protein kinase Src|22.214.171.124|Proto-oncogene c-Src|pp60c-src|p60-Src|SRC1|SRC
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 20q11.23
Immunogen: Synthetic peptide, corresponding to amino acids 390-430 of Human c-Src.
Description: The major translational products of each of the eight members of the Src gene family identified to date are membrane-associated tyrosine protein kinases that lack transmembrane and external amino acid sequences, thereby distinguishing this group from the receptor class of tyrosine kinases. Members of this group include c-Src, c-Yes, Fyn, Lck, Lyn, Blk and c-Fgr. The major Src gene encoded protein, c-Src (also designated pp60Src, Src p60 and proto-oncogene tyrosine protein kinase Src) is expressed in a broad range of tissue and cell types, although the highest levels of c-Src are detected in neuronal tissues and platelets. c-Src may play a role in events associated with both neuronal differentiation and maintenance of mature neuronal cell functions.
TARGETWeight: 60 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: c-Src (L412) polyclonal antibody detects endogenous levels of Src protein.
Description: Immunohistochemistry (IHC) analyzes of c-Src (L412) pAb in paraffin-embedded breast carcinoma tissue.
Description: Western blot (WB) analysis of c-Src (L412) pAb at 1:500 dillutionLane1:Hela whole cell lysate(40μg)Lane2:PC12 whole cell lysate(40μg)Lane3:NIH-3T3 whole cell lysate(40μg)