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Anti-MYC Antibody BHA11300411
Alternative: Myc proto-oncogene protein|Class E basic helix-loop-helix protein 39|bHLHe39|Proto-oncogene c-Myc|Transcription factor p64|MYC|BHLHE39
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 8q24.21
Immunogen: Synthetic peptide, corresponding to amino acids 341-390 of Human Myc.
Description: c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Myc proteins are nuclear proteins with relatively short half lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas. The presence of three sequence motifs in the c-Myc COOH terminus, including the leucine zipper, the helix-loop-helix and a basic region provided initial evidence for a sequence-specific binding function.
TARGETWeight: 49, 57, 65 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.Specificity: Myc (R367) polyclonal antibody detects endogenous levels of proto-oncogene c-Myc protein.
Description: Immunohistochemistry (IHC) analyzes of Myc (R367) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.